The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 279: 7-alpha-hydroxysteroid dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cholate 7-alpha-dehydrogenase activity GO:0008709
Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH.
|
57 |
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
(47 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
57 |
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
(47 more) |
|
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
|
57 |
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
(47 more) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Bile acid catabolic process GO:0030573
The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.
|
57 |
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
(47 more) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
57 |
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
(47 more) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
57 |
P0AET8 (/HDA)
P0AET8 (/HDA)
P0AET8 (/HDA)
P0AET8 (/HDA)
P0AET8 (/HDA)
P0AET8 (/HDA)
P0AET8 (/HDA)
P0AET8 (/HDA)
P0AET8 (/HDA)
P0AET8 (/HDA)
(47 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
57 |
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
P0AET8 (/IDA)
(47 more) |
