CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Succinate--CoA ligase [ADP-forming] subunit alpha

Enzyme Information

6.2.1.4
Succinate--CoA ligase (GDP-forming).
based on mapping to UniProt P09143
GTP + succinate + CoA = GDP + phosphate + succinyl-CoA.
-!- Itaconate can act instead of succinate and ITP instead of GTP.

UniProtKB Entries (1)

P25126
SUCC_THETH
Thermus thermophilus
Succinate--CoA ligase [GDP-forming] subunit beta

PDB Structure

PDB 3UFX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Biochemical and structural characterization of the GTP-preferring succinyl-CoA synthetase from Thermus aquaticus.
Joyce, M.A., Hayakawa, K., Wolodko, W.T., Fraser, M.E.
Acta Crystallogr.,Sect.D
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