CATH Domain 2zcvA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	Quinone oxidoreductase 2

Enzyme Information

1.6.5.2

NAD(P)H dehydrogenase (quinone).

based on mapping to UniProt P39315

NAD(P)H + a quinone = NAD(P)(+) + a hydroquinone.

-!- The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone. -!- The animal, but not the plant, form of the enzyme is inhibited by dicoumarol. -!- Formerly EC 1.6.99.2.

UniProtKB Entries (1)

P39315

QOR2_ECOLI

Escherichia coli K-12

Quinone oxidoreductase 2

PDB Structure

PDB	2ZCV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of a new type of NADPH-dependent quinone oxidoreductase (QOR2) from Escherichia coli Kim, I.K., Yim, H.S., Kim, M.K., Kim, D.W., Kim, Y.M., Cha, S.S., Kang, S.O. J.Mol.Biol.