CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Alanine dehydrogenase |
Enzyme Information
| 1.4.1.1 |
Alanine dehydrogenase.
based on mapping to UniProt P9WQB1
L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH.
|
UniProtKB Entries (1)
| P9WQB1 |
DHA_MYCTU
Mycobacterium tuberculosis H37Rv
Alanine dehydrogenase
|
PDB Structure
| PDB | 2VOJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of the Mycobacterium Tuberculosis Secretory Antigen Alanine Dehydrogenase (Rv2780) in Apo and Ternary Complex Forms Captures "Open" and "Closed" Enzyme Conformations.
Proteins: Struct., Funct., Bioinf.
|
