CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | 2-dehydropantoate 2-reductase |
Enzyme Information
| 1.1.1.169 |
2-dehydropantoate 2-reductase.
based on mapping to UniProt P0A9J4
(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH.
|
UniProtKB Entries (1)
| P0A9J4 |
PANE_ECOLI
Escherichia coli K-12
2-dehydropantoate 2-reductase
|
PDB Structure
| PDB | 2OFP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Escherichia coli Ketopantoate Reductase in a Ternary Complex with NADP+ and Pantoate Bound: SUBSTRATE RECOGNITION, CONFORMATIONAL CHANGE, AND COOPERATIVITY.
J.Biol.Chem.
|
