CATH Domain 2foiB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	Enoyl-[acyl-carrier-protein] reductase [NADH]

Enzyme Information

UniProtKB Entries (1)

C6KSZ2_PLAF7

Plasmodium falciparum 3D7

Enoyl-acyl carrier reductase

PDB Structure

PDB	2FOI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	X-ray Structural Analysis of Plasmodium falciparum Enoyl Acyl Carrier Protein Reductase as a Pathway toward the Optimization of Triclosan Antimalarial Efficacy. Freundlich, J.S., Wang, F., Tsai, H.C., Kuo, M., Shieh, H.M., Anderson, J.W., Nkrumah, L.J., Valderramos, J.C., Yu, M., Kumar, T.R., Valderramos, S.G., Jacobs, W.R., Schiehser, G.A., Jacobus, D.P., Fidock, D.A., Sacchettini, J.C. J.Biol.Chem.