CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Shikimate 5-dehydrogenase

Enzyme Information

1.1.1.25
Shikimate dehydrogenase.
based on mapping to UniProt P44774
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

P44774
SHDHL_HAEIN
Haemophilus influenzae Rd KW20
Shikimate dehydrogenase-like protein HI_0607

PDB Structure

PDB 1NPY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of a Novel Shikimate Dehydrogenase from Haemophilus influenzae.
Singh, S., Korolev, S., Koroleva, O., Zarembinski, T., Collart, F., Joachimiak, A., Christendat, D.
J.Biol.Chem.
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