CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | NADPH:adrenodoxin oxidoreductase, mitochondrial |
Enzyme Information
| 1.18.1.6 |
Adrenodoxin-NADP(+) reductase.
based on mapping to UniProt P08165
2 reduced adrenodoxin + NADP(+) = 2 oxidized adrenodoxin + NADPH.
-!- The enzyme, which transfers electrons from NADPH to adrenodoxin molecules, is the first component in the mitochondrial cytochrome P450 electron transfer systems, and is involved in the biosynthesis of all steroid hormones.
|
UniProtKB Entries (1)
| P00257 |
ADX_BOVIN
Bos taurus
Adrenodoxin, mitochondrial
|
PDB Structure
| PDB | 1E6E |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Adrenodoxin Reductase-Adrenodoxin Complex Structure Suggests Electron Transfer Path in Steroid Biosynthesis.
J.Biol.Chem.
|
